What is a pharmaceutical intermediate


Release time:

2023-03-10

Source:

network

China requires more than 2000 types of raw materials and intermediates that are matched with chemical industry every year, with a demand of over 2.5 million tons. After more than 30 years of development, the chemical raw materials and intermediates required for pharmaceutical production in China can basically be matched, with only a small portion needing to be imported. Moreover, due to China's abundant resources and low raw material prices, many intermediates have been exported in large quantities. So, what are the development opportunities faced by China's pharmaceutical intermediate industry?

What is a pharmaceutical intermediate

China requires more than 2000 types of raw materials and intermediates that are matched with chemical industry every year, with a demand of over 2.5 million tons. After more than 30 years of development, the chemical raw materials and intermediates required for pharmaceutical production in China can basically be matched, with only a small portion needing to be imported. Moreover, due to China's abundant resources and low raw material prices, many intermediates have been exported in large quantities. So, what are the development opportunities faced by China's pharmaceutical intermediate industry?

Increased demand

our country β- After nearly 50 years of development, lactam antibiotics have formed a complete production system. In 2012, almost all β- Lactam antibiotics (except for those within the patent period) can be produced in China, and the cost is very low. Penicillin production ranks first in the world, and a large number of them are exported to the international market; Cephalosporins are basically self-sufficient and can also compete for some exports.

In 2012, compared to β- All the supporting intermediates of lactam antibiotics can be produced in China. Except for the mother core 7-ACA and 7-ADCA of semi synthetic antibiotics that need to be imported, all the side chain intermediates can be produced and exported in large quantities.

with β- For example, phenylacetic acid, the main supporting intermediate of lactam antibiotics, has nearly 30 phenylacetic acid manufacturers in China with a total annual production capacity of about 20000 tons. But most enterprises are relatively small in scale, with an annual output of 2000 tons, while most others produce hundreds of tons per year. In 2003, the total demand for phenylacetic acid in China was about 14000 tons, with a consumption structure of penicillin G accounting for 85%, other pharmaceuticals accounting for 4%, spices accounting for 7%, and pesticides and other fields accounting for 4%.

With the development of domestic industries such as spices, pharmaceuticals, and pesticides, the demand for phenylacetic acid will further increase. It is expected that by 2005, China's pharmaceutical industry will consume approximately 14000 tons of phenylacetic acid, the pesticide industry will consume 500 tons, and the spice industry will consume approximately 2000 tons. Combined with the consumption in other fields, it is expected that the total demand for phenylacetic acid in China will reach 18000 tons in 2005.