Propylthiouracil Propylthiouracil

Propylthiouracil

Propylthiouracil curbs iodization of tyrosine inside the thyroid and condensation of iodotyrosine by curbing the peroxidase system inside the thyroid, so as to curb the synthesis of thyroid hormones. Large dosage of Propylthiouracil (daily dosage >700 mg) will reduce conversion from T4 to T3 in surrounding tissues. This product also plays the immunosuppression role.

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Propylthiouracil

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Pharmaceutical intermediates

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Product Details

Propylthiouracil curbs iodization of tyrosine inside the thyroid and condensation of iodotyrosine by curbing the peroxidase system inside the thyroid, so as to curb the synthesis of thyroid hormones. Large dosage of Propylthiouracil (daily dosage >700 mg) will reduce conversion from T4 to T3 in surrounding tissues. This product also plays the immunosuppression role.

● CAS：51-52-5

● Molecular weight：70.23200

● PSA：80.74000

● Molecular formula：C7H10N2OS

● Appearance and description： white to grayish white crystalline powder

● Density：1.24g/m³

● Boiling point：355.2℃ at 760mmHg

● Melting point：218-220℃(lit.)

● Flashing point：300℃

● Refractive index：1.609

● Water solubility：1.1 g/L

● Stability：Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, strong bases. Light sensitive.

● Storage condition：Store in a cool, dry place. Keep container closed when not in use. Hormones and antibiotics room.

● Safety information

RTECS No.YR1400000

Safety instruction：S36/37-S45

Hazard category code：R22; R40

WGK Germany：3

Customs code：2933599090

Hazardous product mark：Xn

● Production method

It is produced through condensation of β-oxohexanoate and thiourea or condensation of ethyl butyryl acetate and thiourea.

● Purpose

Medicine biochemical intermediates.

● Synthetic route

Propylthiouracil

● Chromatogram

 

Propylthiouracil

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Tel：+86 13526918902 Manager Wu

Tel：+86 13838822280 Manager Duan

Tel：+86 13333887633 Manager Zhu

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Add：North of Taihe Road, Industrial Cluster District, Guanyintang Town, Shanzhou District, Sanmenxia City

 

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